Synthesis and Characterization of Chitosan- Polyvinyl alcohol Blend Modified by Genipin and Nanohydroxyapatite for Bone Tissue Engineering

Chitosan/PVA blend, Genipin, Nanohydroxyapate, Bone engineering, Degradation.

Authors

  • Ishraq A. Kadhim University of technology
  • Zuhair J. Abdul Ameer
  • Assel B. Alzubaidi

Abstract

Use nanohydroxyapatite into the polymeric matrix as bioactive material for bone tissue engineering has enormous therapeutic potential because beneficial properties biocompatibility, biodegradability, and consider a major inorganic constituent of the bone matrix. The blended films of Chitosan and Polyvinyl alcohol with Genipin as cross-link agent were studied with and without addition Nanohydroxyapatite. Samples were prepared by solvent casting. The resulting films blended composite were characterized by Fourier transfer infrared (FTIR) spectroscopy, degradation behavior, swelling degree and tensile strength. Degree of swelling, and weight loss of the films blended composite was decreased with an increase of genipin and nanohydroxyapatie concentrations while tensile strength was increased with an increase of genipin and nanohydroxyapaite concentrations. The results showed that the chitosan composite could be used as effective biomaterials for bone regeneration engineering with different degradation rates.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Published

2019-11-25

How to Cite

Kadhim, I. A., Abdul Ameer, Z. J. ., & Alzubaidi, A. B. . (2019). Synthesis and Characterization of Chitosan- Polyvinyl alcohol Blend Modified by Genipin and Nanohydroxyapatite for Bone Tissue Engineering: Chitosan/PVA blend, Genipin, Nanohydroxyapate, Bone engineering, Degradation. Engineering and Technology Journal, 37(11A), 470-474. Retrieved from http://engtechjournal.org/index.php/et/article/view/333